For a brief introduction and guide to abbreviations, see Laboratory Tests: General Remarks.
Antinuclear antibodies (ANA) [S/P]
Reference range, target level, or decision threshold
As provided by laboratory, depending on method!!!
Indirect immunofluorescence on HEp-2000: Titer <1:160
Interpretation of results
↑ SLE, drug-induced lupus erythematosus, antiphospholipid syndrome, scleroderma, polymyositis and dermatomyositis, Sjögren syndrome, mixed connective tissue disease, rheumatoid arthritis, juvenile idiopathic arthritis, Raynaud phenomenon, other clinical conditions (where it is usually clinically insignificant) including infections (eg, TB, viral hepatitis, syphilis, parasitic diseases), malignancies (eg, breast cancer, prostate cancer, leukemia, Hodgkin lymphoma), liver and pulmonary diseases, skin diseases (eg, psoriasis, lichen planus), solid organ transplant, use of certain drugs (particularly hydralazine), other autoimmune conditions (eg, primary cholangitis, Addison disease, Hashimoto thyroiditis, immune thrombocytopenic purpura, autoimmune hemolytic anemia, type 1 DM), HIV infection, healthy individuals
