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Chapter Editors: Debarati Bhar, Shambo Samrat Samajdar, Tanuka Mandal, Sattik Siddhanta
How to Cite This Chapter: Don-Wauchope A, Chetty VT, Ivica J, Kavsak P, Khan WI, Lafreniere M, Nouri K, Solnica B. Apolipoprotein B (ApoB). McMaster Textbook of Internal Medicine. Kraków: Medycyna Praktyczna. https://empendium.com/mcmtextbook-sae/chapter/B78.1269.3.7.174. Accessed September 20, 2024.
Last Updated: May 9, 2022
Last Reviewed: May 9, 2022
Chapter Information
McMaster Textbook of Internal Medicine Editorial Offices
Editorial Office (Canada)
Authors: Andrew Don-Wauchope, Vasudhevan T. Chetty, Joško Ivica, Peter Kavsak, Waliul I. Khan, Matthew Lafreniere, Kazem Nouri
Editorial Office (Poland)
Authors: Bogdan Solnica
For a brief introduction and guide to abbreviations, see Laboratory Tests: General Remarks.
Analyte [material]
Apolipoprotein B (ApoB) [S/P]
Reference range, target level, or decision threshold
Depends on cardiovascular riskCPG:
Extremely high: <55 mg/dL
Very high: <65 mg/dL
High: <80 mg/dL
Moderate: <100 mg/dL
There are age-specific reference intervals for pediatric patients.
Interpretation of results
↑ Familial hypercholesterolemia, familial apolipoprotein B100 deficiency, polygenic hypercholesterolemia, hypothyroidism, nephrotic syndrome, CKD, liver diseases with cholestasis, drugs (progestogens, glucocorticoids, protease inhibitors used in HIV infection)
↓ Hyperthyroidism, advanced cirrhosis and other severe liver injury, sepsis, cachexia