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Chapter Editors: Debarati Bhar, Shambo Samrat Samajdar, Tanuka Mandal, Sattik Siddhanta
How to Cite This Chapter: Don-Wauchope A, Chetty VT, Ivica J, Kavsak P, Khan WI, Lafreniere M, Nouri K, Solnica B. Alkaline Phosphatase (ALP). McMaster Textbook of Internal Medicine. Kraków: Medycyna Praktyczna. https://empendium.com/mcmtextbook-sae/chapter/B78.1269.3.7.83. Accessed September 20, 2024.
Last Updated: May 9, 2022
Last Reviewed: May 9, 2022
Chapter Information
McMaster Textbook of Internal Medicine Editorial Offices
Editorial Office (Canada)
Authors: Andrew Don-Wauchope, Vasudhevan T. Chetty, Joško Ivica, Peter Kavsak, Waliul I. Khan, Matthew Lafreniere, Kazem Nouri
Editorial Office (Poland)
Authors: Bogdan Solnica
For a brief introduction and guide to abbreviations, see Laboratory Tests: General Remarks.
Analyte [material]
Alkaline phosphatase (ALP) [S/P]
Reference range, target level, or decision threshold
<270 IU/L
There are age- and sex-specific reference intervals for ALP.!!!
Interpretation of results
↑ Cholestasis (drug induced, biliary obstruction, primary biliary cirrhosis, primary cholangitis, vanishing bile duct syndrome, mild recurrent cholestasis), hepatitis, cirrhosis, hepatic infiltrates (sarcoidosis, TB, fungal infections, other granulomatous diseases, amyloidosis), hepatocellular carcinoma, metastases to liver, bone diseases, CKD, heart failure, lymphomas and other malignancies, infection, inflammation