Thrombocytopenia Caused by Excess Destruction of Platelets

Chapter: Thrombocytopenia Caused by Excess Destruction of Platelets
McMaster Section Editor(s): Mark Crowther
Section Editor(s) in Interna Szczeklika: Andrzej Hellmann, Bogdan Ochrem
McMaster Author(s): Mark Crowther
Author(s) in Interna Szczeklika: Krystyna Zawilska†, Wojciech Młynarski
† Deceased.
Additional Information


Typical features of thrombocytopenia caused by excess destruction of platelets include increased mean platelet volume and bone marrow megakaryocyte counts as well as a reduced platelet life-span, which lead to low peripheral platelet counts despite a marked increase in bone marrow platelet production.

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