Sodium Disturbances

How to Cite This Chapter: Mathew A, Kokot F, Franek E, Drabczyk R. Sodium Disturbances. McMaster Textbook of Internal Medicine. Kraków: Medycyna Praktyczna. Accessed January 18, 2021.
Last Updated: June 14, 2018
Last Reviewed: May 17, 2019
Chapter Information

Physiologic BackgroundTop

The body of an average adult weighing 70 kg contains ~4200 mmol (~60 mmol/kg) of sodium. A total of 91% of the body sodium is in the extracellular fluid (ECF) and the remainder is the intracellular fluid (ICF).

Dietary sodium intake is 80 to 160 mmol/d. In individuals with a normal sodium balance, 95% of dietary sodium is filtered into the renal tubule, 4.5% with feces, and 0.5% through the skin. Less than 1% of sodium filtered into the renal tubule is excreted with urine, while the remaining sodium is reabsorbed.

We would love to hear from you

  • Do you have any comments?
  • Have you found a mistake?
  • Would you like to suggest a feature?

We use cookies to ensure you get the best browsing experience on our website. Refer to our Cookies Information and Privacy Policy for more details.