What is the most important change in the management of type 2 diabetes according to the 2018 consensus report by the American Diabetes Association (ADA) and the European Association of the Study of Diabetes (EASD)?
Sodium-glucose cotransporter 2 (SGLT-2) inhibitors increase renal glucose excretion. Can they be used in older patients with diabetes who often have bacterial colonization but no urinary tract infections?
What are the treatment options for inhibiting the synthesis and secretion of new hormones in severe hyperthyroidism? How much time is needed to see clinical outcomes?
Why is the Burch-Wartofsky Point Scale based only on clinical and physical criteria? How accurate are the estimates?
What are the key diagnostic criteria for thyroid storm? What signs and symptoms are the most alarming and require immediate medical attention?
Should patients with thyroid emergencies (myxedema coma, thyroid storm) be treated in the intensive care unit (ICU)? What parameters and laboratory tests should be monitored?
Can we define an age limit over which treatment of obesity is no longer beneficial?
An older patient with an acute episode of atrial fibrillation treated with amiodarone in an emergency department setting develops signs and symptoms of thyrotoxicosis. The patient needs urgent computed tomography angiography (CTA). What should we do thyroid-wise?
Are there any new drugs that could be used in patients with type 2 diabetes mellitus to reduce weight?
Is there still a place for sulfonylureas in the management of older patients with diabetes?
McMaster Textbook of Internal Medicine acknowledges the important contribution of Cochrane Canada and its authors in development of the textbook.
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