Reliability of TSH measurements

René Rodríguez-Gutiérrez

Is the thyroid-stimulating hormone (TSH) level a stable parameter? Do laboratory errors occur? Is every measurement reliable?

René Rodríguez-Gutiérrez: I will say that definitely TSH [levels] can vary. The recommendation for this is once you have a first set of tests that are compatible with subclinical hypothyroidism, the recommendation is always to repeat, usually within a month or 3 months. In case of pregnancy or infertility, it can be done earlier, but definitely one set of TSH values is not enough.

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