Clinical and laboratory features which may assist in differentiating among DIC, TTP, HUS, and CAPS

Table 9.6-3. Clinical and laboratory features which may assist in differentiating among DIC, TTP, HUS, and CAPS
Clinical features	DIC	TTP	HUS	CAPS
CNS manifestations	+/−	++	+/−	++
Renal impairment	+/−	+/−	+++	++
Liver impairment	+/−	+/−	+/−	+
Hypertension	−	−/+	+/−	−
Fever	+/−	+/−	−/+	−/+
Hemolysis	+	+++	++	+
Thrombocytopenia	+++	+++	++	++
Coagulopathy	+++	−	−	+/−
Adapted from Br J Haematol. 2003;120(4):556-73.
CAPS, catastrophic antiphospholipid syndrome; CNS, central nervous system; DIC, disseminated intravascular coagulation; HUS, hemolytic-uremic syndrome; TTP, thrombotic thrombocytopenic purpura.