Publications of the Week: Glucocorticoids in severe CAP A digest of noteworthy publications from McMaster experts. This week’s focus: effects of the addition of hydrocortisone to usual care on mortality in severe community-acquired pneumonia (CAP).
Recent advances relevant for critical care If you were to name the 3 most important recent advances in critical care that are relevant for everyday practice, what would they be?
High-dose dual therapy for H pylori High-dose amoxicillin–PPI dual therapy is cheaper and easy to perform. Can it be used as the first-choice regimen for Helicobacter pylori eradication in countries with high rates of bacterial resistance to clarithromycin?
Recent advances in allergy and immunology If you were to name the 3 most important recent advances in the fields of allergy and immunology that are relevant for everyday practice, what would they be?
Chronic seizure management in patients with drug-resistant epilepsy We have a broad and still growing selection of antiseizure medications available, and yet drug resistance remains a challenge in roughly a third of patients with epilepsy. Why is this rate so high and how can we improve chronic seizure management in these patients?
Recent advances in generating clinical practice guidelines You are advising people all over the world on how to generate clinical practice guidelines (CPGs). What have been the most important advances in this area over the last few years?
Unexplained increased D-dimer levels Is an unexplained increase in the D-dimer level an indication to test for thrombophilia? Is it an indication to introduce antithrombotic prophylaxis?
Climate change and the spread of infectious diseases What is the impact of ongoing climate changes on the spread of infectious diseases? Are these phenomena relevant to countries in temperate climate zones?
Liver biopsy for NASH diagnosis When should a patient with hepatic steatosis be referred for liver biopsy necessary to diagnose NASH?
Managing sepsis according to the latest Surviving Sepsis practice guidelines A lecture by Dr Simon Oczkowski from McMaster University delivered at the McMaster International Review Course in Internal Medicine (MIRCIM) in 2022.
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