According to the EULAR guidelines, in gout flares colchicine is recommended within 12 hours of the onset of symptoms. Because most patients frequently present after this time, the recommendation concerns self-administration of colchicine and treatment of subsequent flares. Can we use low-dose colchicine if the patient presents after 12 hours from the onset of symptoms? Or should we prefer nonsteroidal anti-inflammatory drugs or steroids?
Should every pregnant woman with thyroid-stimulating hormone (TSH) levels >2.5 mIU/L be treated with levothyroxine even in the absence of anti-thyroid peroxidase antibodies and antithyroglobulin antibodies?
As the Assistant Dean for Continuing Health Sciences Education, you are responsible for continuing professional development (CPD) and continued medical education (CME) at the Faculty of Health Sciences at McMaster University. For those who are unfamiliar with this part of the continuum of medical education, can you explain what CPD and CME are?