|
Class |
Action |
Drugs | |
|
I |
Sodium channel blockade |
| |
|
Ia |
Moderate phase 0 depression, prolonging of action potential |
Quinidine, procainamide, disopyramide | |
|
Ib |
Minimal effect on phase 0, no change in duration of action potential |
Lidocaine, mexiletine | |
|
Ic |
Marked phase 0 depression, conduction slowing, little effect on repolarization |
Flecainide, propafenone | |
|
II |
Beta-adrenergic blockade |
Propranolol, metoprolol, atenolol, esmolol, bisoprolol | |
|
III |
Potassium channel blockade |
Amiodarone, sotalol, bretylium, ibutilide | |
|
IV |
Calcium channel blockade |
Verapamil, diltiazem | |