Table 19.11-2. Indications for long-term oxygen therapy for COPD

PaO2

SpO2 or SaO2

Indications

≤55 mm Hg

≤88%

Always

55-59 mm Hg

88%-89%

If one of these is present:

– Cor pulmonale

– Pulmonary hypertension

– Persistent erythrocytosis (hematocrit >55%)

≥60 mm Hg

≥90%

If one of these occurs:

– Exercise limited by hypoxemia (SpO2 <88%)

– Nocturnal hypoxemia

Based on Global Initiative for Chronic Obstructive Lung Disease (GOLD). Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Pulmonary Disease: 2020 Report. http://www.goldcopd.org

COPD, chronic obstructive pulmonary disease; PaO2, partial pressure of oxygen in arterial blood; SaO2, direct measurement of hemoglobin oxygen saturation in arterial blood; SpO2, measurement of hemoglobin oxygen saturation in arterial blood using pulse oximetry.