Table 16.3-1. First-line medication for specific anxiety and related disorders

Disorder

First-line medications

Panic disorder

Paroxetinea, sertraline, escitalopram

Social anxiety disorder

Paroxetinea, sertraline, escitalopram, pregabalin

Generalized anxiety disorder

Paroxetinea, sertraline, pregabalin

Obsessive-compulsive disorder

Fluoxetine, fluvoxamine, sertraline

Posttraumatic stress disorder

Paroxetinea, sertraline, prazosin

a Paroxetine should be avoided in children and adolescents aged <18 years and during pregnancy (United States Food and Drug Administration category D drug).