Currently available biologic agents used in asthma - McMaster Textbook of Internal Medicine

Table 17.1-2. Currently available biologic agents used in asthma
Mechanism of action	Medication	Dosage
Anti-IgE monoclonal antibody	Omalizumab	75-600 mg SC (based on baseline serum IgE level), 1-4 injections every 2-4 weeks
Anti-IL-5 monoclonal antibodies	Mepolizumab	100 mg SC every 4 weeks
Anti-IL-5 monoclonal antibodies	Reslizumab	3 mg/kg IV every 4 weeks
Anti-IL-5 receptor monoclonal antibody	Benralizumab	30 mg SC every 4 weeks for 3 months, then every 8 weeks
Anti-IL-4 receptor monoclonal antibody	Dupilumab	Dose 1: 400-600 mg; then 200 or 300 mg SC every 2 weeks
IL, interleukin; IV, intravenous; SC, subcutaneous.