Pemphigus foliaceus (Figure 2) |
– No mucosal involvement – Usually milder skin lesions on the chest, back, face, and scalp |
Pemphigus herpetiformis |
– Characterized by grouped, pruritic, vesiculobullous lesions in herpetiform and annular arrangement – Mucosal involvement is uncommon |
Pemphigus vegetans (Figure 3) |
– Characterized by hyperkeratotic, verrucous, vegetative plaques, mostly affecting intertriginous areas – Involvement of oral mucosa is common |
IgA pemphigus (subcorneal pustular dermatosis and intraepidermal neutrophilic IgA dermatosis) |
Groups of vesicles and pustules on the erythematous background, mostly on the trunk, proximal extremities, and in intertriginous areas |
Paraneoplastic pemphigus |
– Severe, painful, hemorrhagic oral erosions and ulcerations extending to lips – Polymorphic skin lesions (eg, flaccid pemphigus-like blisters; tense pemphigoid-like bullae; erythema multiforme–like, graft-versus-host disease–like, and purple, lichen planus–like lesions) – Severe bronchiolitis (bronchiolitis obliterans) can also develop |