Criteria |
Score | |
Autoantibodies (max, 2 points) |
| |
ANA or SMA titer ≥1:40 |
1 | |
ANA or SMA titer ≥1:80, anti-LKM1 titer ≥1:40, or positive anti-SLA/LP |
2 | |
IgG level |
| |
>ULN (16 g/L) |
1 | |
>1.1 × ULN (18 g/L) |
2 | |
Histology |
| |
Consistent with autoimmune hepatitis |
1 | |
Typical for autoimmune hepatitis |
2 | |
Viral hepatitis excluded |
2 | |
Interpretation: Score 6: Probable autoimmune hepatitis Score 7-8: Definite autoimmune hepatitis | ||
Based on Hepatology. 2008;48(1):169-76. | ||
ANA, antinuclear antibody; anti-LKM1, antibody to type 1 liver and kidney microsomal antigen; anti-SLA/LP, antibody to soluble liver antigen/liver-pancreas; SMA, smooth muscle antibody; ULN, upper limit of normal. |