Familial |
Cystinosisa, Wilson disease, hereditary fructose intolerance, tyrosinemia, galactosemia, Lowe disease, Dent disease |
Dysproteinemias |
Multiple myeloma (LCDD)a, amyloidosis |
Drugs |
Acetazolamidea, topiramate, NRTIs (tenofovira, adefovir, didanosine, lamivudine), chemotherapeutics (ifosfamide, platinum-based chemotherapy) |
Heavy metals |
Leada, mercury, copper (Wilson disease) |
Tubulointerstitial diseases |
Renal transplant, Balkan/Chinese herb nephropathy (aristolochic acid toxicity), medullary cystic kidney disease |
Other |
Vitamin D deficiency |
Familial causes are more prevalent among the pediatric population but can remain undiagnosed until later in life. | |
a The more common etiologies. | |
LCDD, light chain deposition disease; NRTI, nucleoside reverse transcriptase inhibitor. |