Table 10.6-1. Tetanus postexposure prophylaxis

History of tetanus vaccination

Clean, minor wounds

Other wounds (contaminated with soil or feces or with necrotic tissue present)

Tetanus vaccine required?

Tetanus Ig required?

Tetanus vaccine required?

Tetanus Iga required?

Unknown vaccination history or <3 doses

Yes

No

Yes

Yes

Completed primary vaccine series with most recent dose or booster dose <5 years ago

No

No

No

Nob

Completed primary vaccine series with most recent dose or booster dose between 5 and 10 years ago

No

No

Yes

Nob

Completed primary vaccine series with most recent dose or booster dose >10 years ago

Yes

No

Yes

Nob

a The Ig dose is 250 IU administered IM.

b Patients with humoral immune deficiencies should also receive Ig.

Adapted from the Public Health Agency of Canada’s Canadian Immunization Guide. Available at www.canada.ca.

Ig, immunoglobulin; IM, intramuscular.