Nonantidiabetic drugs causing hypoglycemia with associated likelihood based on quality of evidence in medical literature

Table 6.2-2. Nonantidiabetic drugs reported to cause hypoglycemia with indication of the QoE supporting such association
Moderate QoE	Low QoE	Very low QoE
– Cibenzoline – Gatifloxacin – Pentamidine – Quinine – Indomethacin – Glucagon (during endoscopy)	– Chloroquineoxaline sulfonamide – Artesunate, artemisinin, artemether – IGF-1 – Lithium – Propoxyphene (dextropropoxyphene)	– ACEIs – ARBs – Beta-adrenergic receptor antagonists – Levofloxacin – Disopyramide – TMP/SMX – Heparin – 6-mercaptopurine
Adapted from Journal of Clinical Endocrinology & Metabolism, March 2009, 94(3): 709-728.
ACEI, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor blocker; IGF-1, insulin-like growth factor 1; QoE, quality of evidence; TMP/SMX, trimethoprim/sulfamethoxazole.