Table 7.2-2. Conditions associated with esophageal eosinophilia (other than EoE or GERD)

Associated conditions

Comment

Eosinophilic gastritis, gastroenteritis, or colitis

With esophageal involvement

Crohn disease

With esophageal involvement

Esophageal motor disorders

– Achalasia of cardia

– Esophagogastric outlet obstruction

– Esophageal body dysmotility

Infections

Viral, fungal, bacterial

Medications

– Drug hypersensitivity reactions

– Pill esophagitis

Autoimmune disorders

– Connective tissue disorders

– Vasculitides

Dermatologic conditions

– With esophageal involvement

– Pemphigus vulgaris

Graft-versus-host disease

 

Mendelian disorders

– Marfan syndrome type II

– Hyper-IgE syndrome

– PTEN hamartoma tumor syndrome

– Netherton syndrome

– Severe atopy metabolic wasting syndrome

HES

– Primary (neoplastic) HES

– Secondary (reactive) HES

– Idiopathic HES

Hypermobility syndromes

Ehlers-Danlos syndrome

EoE, eosinophilic esophagitis; GERD, gastroesophageal reflux disease; HES, hypereosinophilic syndrome; PTEN, phosphatase and tensin homolog.