Medications associated with vitamin D deficiency - McMaster Textbook of Internal Medicine

Table 6.6-1. Medications associated with vitamin D deficiency
Name	Mechanism
Antiepileptic drugs	Cause increased catabolism of 25-hydroxyvitamin D and 1,25-dihydroxycholecalciferol
Glucocorticoids	Decrease calcium absorption in the intestines, increased renal excretion of calcium, and inhibition of 1-alpha-hydroxylase
Orlistat	Impairs vitamin D absorption in the gastrointestinal tract
Bile acid sequestrants	Impairs vitamin D absorption in the gastrointestinal tract
Ketoconazole	Inhibits 1-alpha-hydroxylase