Drug

Dosing on day 1 (the day of chemotherapy)

Dosing on subsequent days

Aprepitant 

or

Netupitant (in combination with palonosetron)

or

Fosaprepitant

125 mg PO in a single dose

300 mg + 0.5 mg PO in a single dose

150 mg IV in a single dose

80 mg PO daily (on days 2-3)

Ondansetron

or

Palonosetron

8 mg PO bid or 8 mg IV in a single dose

0.5 mg PO in a single dose

None recommended

Dexamethasone

12 mg PO or 10 mg IV in a single dose

8 mg PO or 10 mg IV until 2 days after the last dose of chemotherapy

Olanzapine

5 mg PO in a single dose

5 mg PO daily or 2.5 mg PO bid for days of chemotherapy and up to 2-3 days after chemotherapy