Table 6.1-2. Medications/substances that may interfere with biochemical testing

 

Normetanephrines

Metanephrines

Plasma

Urine

Plasma

Urine

Acetaminophen

­­↑↑

­­↑↑

No change

No change

Labetalol

No change

­­↑↑

No change

­­↑↑

Sotalol

No change

­­↑↑

No change

­­↑↑

Alpha-methyldopa

­­↑↑

­­↑↑

No change

No change

Tricyclic antidepressants

­­↑↑

­­↑↑

No change

No change

Phenoxybenzamine

­­↑↑

↑↑­­

No change

No change

Monoamine oxidase inhibitors

­­↑↑

↑↑­­

­­↑↑

↑↑­­

Sympathomimetics

­↑

­↑

­↑

­↑

Levodopa

­↑

­­↑↑

­↑

­↑

Buspirone

No change

No change

­­↑↑

↑↑­­

Cocaine

­­↑↑

↑↑­­

­↑

­↑