Table 6.7-1. Assessment of the risk of thyrotoxic crisis based on the Burch-Wartofsky criteria

Temperature

38-38.5 degrees Celsius

5 points

38.6-39 degrees Celsius

10 points

39.1-39.5 degrees Celsius

15 points

39.6-40 degrees Celsius

20 points

40.1-40.6 degrees Celsius

25 points

>40.6 degrees Celsius

30 points

Central nervous system disturbance

Absent

0 points

Mild (agitation)

10 points

Moderate (delirium, psychosis, extreme lethargy)

20 points

Severe (seizure, coma)

30 points

Gastrointestinal-hepatic dysfunction

Absent

0 points

Moderate (diarrhea, abdominal pain, nausea/vomiting)

10 points

Severe (jaundice)

20 points

Cardiovascular dysfunction

Tachycardia (beats/min)

<90/min

0 points

90-109/min

5 points

110-119/min

10 points

120-129/min

15 points

130-139/min

20 points

≥140/min

25 points

Congestive heart failure

Absent

0 points

Mild (pedal edema)

5 points

Moderate (bibasilar rales)

10 points

Severe (pulmonary edema)

15 points

Atrial fibrillation

Absent

0 points

Present

10 points

A precipitating event in patients with untreated or inappropriately treated hyperthyroidism: acute infection, trauma, surgery, childbirth, ketoacidosis, myocardial infarction, stroke or transient ischemic attack, radioiodine treatment (rarely), or administration of iodinated contrast media

Absent

0 points

Present

10 points

<25 points, unlikely to represent thyrotoxic crisis; 25-44 points, suggestive of impending crisis; ≥45 points, highly suggestive of thyrotoxic crisis; rapid, aggressive specific and supportive treatment required.

Adapted from mdcalc.com.