Primary tumor (T)

Tis

Carcinoma in situ

T1

Tumor <2 cm in greatest dimension

T2

Tumor 2-5 cm in greatest dimension

T3

Tumor >5 cm in greatest dimension

T4

Tumor invading adjacent organs (eg, bladder, vagina)

Regional lymph nodes (N)

N0

No regional lymph node involvement

N1

Metastasis in the perirectal nodes

N2

Metastasis in unilateral internal iliac and/or inguinal nodes

N3

Metastasis in bilateral internal iliac or inguinal nodes

Distant metastases (M)

M0

No distant metastasis

M1

Distant metastasis

Adapted from Clin Med Insights Oncol. 2014 Sep 17;8:113-9. doi: 10.4137/CMO.S13241.

SCC, squamous cell carcinoma; TNM, tumor, node, metastasis.