Table 1.29-1. Common causes of abdominal pain by location

Location

Causes

Right upper quadrant

Cholecystitis, cholangitis, biliary colic, acute hepatitis, pancreatitis, esophagitis, PUD, IBD, intestinal obstruction, retrocecal appendicitis, renal colic, pyelonephritis, subphrenic abscess, right lower lobe pneumonia, congestive heart failure (liver congestion)

Epigastric region

Functional dyspepsia, GERD, drug-induced damage to gastric and duodenal mucosa, PUD, gastroenteritis, diseases of biliary system, acute hepatitis, pancreatitis, pancreatic pseudocysts, cancer (gastric, pancreatic, colorectal), intestinal ischemia, abdominal aortic aneurysm, myocardial infarction

Left upper quadrant

Splenic rupture or infarction, pancreatitis, pancreatic pseudocysts, intestinal ischemia affecting splenic flexure, renal colic, pyelonephritis, subphrenic abscess, left lower lobe pneumonia

Right and left lumbar region

Renal colic, pyelonephritis, renal infarction, IBD, intestinal obstruction, hernia

Umbilical region

Early phase of appendicitis, gastroenteritis, intestinal obstruction, IBD, intestinal ischemia, pancreatitis, abdominal aortic aneurysm, hernia

Right lower quadrant

Appendicitis, disorders of small or large intestine (intestinal obstruction, IBD, ileocecal intussusception), disorders of genitourinary system (renal colic, pyelonephritis, adnexitis, ovarian cyst, ovarian torsion, ovarian rupture, extrauterine pregnancy), abscess (pelvic, lumbar), purulent sacroiliitis, hernia

Hypogastric region

Appendicitis, diverticulitis, intestinal obstruction, IBD, IBS, adnexitis, pelvic inflammatory disease, renal colic, cystitis, pelvic abscess, hernia

Left lower quadrant

Acute diverticulitis, infectious diseases, IBD, sigmoid intussusception, IBS, renal colic, pyelonephritis, adnexitis, ovarian cyst, ovarian torsion, ovarian rupture, extrauterine pregnancy, sacroiliitis

Diffuse pain

Infectious or noninfectious gastroenteritis, intestinal obstruction, peritonitis, urinary tract infection

Pain in dermatomal distribution

Herpes zoster (shingles)

GERD, gastroesophageal reflux disease; IBD, inflammatory bowel disease; IBS, irritable bowel syndrome; PUD, peptic ulcer disease.