Table 6.2-9. Differential diagnosis of neuropathic and ischemic foot

Feature

Foot ischemia

Neuropathic foot

Pain on movement

++

Pain at rest

+++ (if severe)

±

Sensory abnormalities

++

Pulse on the lower extremity

Absent

Present

Skin

Cold

Warm

Bone structure

Normal

Damaged

Lesion type

Gangrene

Ulceration

Lesion location

Depends on location of arterial lesions

Depends on internal and external pressure areas

Pain

Increases with physical activity

Increases with rest, usually appears at night