Parameter |
Iron deficiency anemia |
Anemia of chronic disease |
Thalassemia alpha or beta |
Sideroblastic anemia | |
Anemia severity |
Any |
Rarely Hb <9 g/dL |
Mild (in trait) |
Any | |
MCV |
↓ or ↓↓ |
N or ↓ |
↓↓ |
N, ↓, or ↑ | |
Serum ferritin |
↓ (may be normal or increased with inflammation/liver disease) |
N or ↑ |
N or ↑
|
↑ | |
TIBC |
↑ |
↓ |
N |
N | |
Iron | |||||
Serum |
↓ |
↓ |
N |
↑ | |
Bone marrow |
↓ or absent |
Present |
Present |
Present | |
↓, decreased; ↑, increased; Hb, hemoglobin; MCV, mean corpuscular volume; N, normal; TIBC, total iron-binding capacity. |