|
|
Stage | ||||
|
0 |
I |
II |
III |
IV | |
|
Lymphocytosis |
+ |
+ |
+ |
+ |
+ |
|
Lymphadenopathy |
– |
+ |
+/– |
+/– |
+/– |
|
Splenomegaly or hepatomegaly |
– |
– |
+ |
+/– |
+/– |
|
Anemia (hemoglobin <11 g/dL) |
– |
– |
– |
+ |
+/– |
|
Thrombocytopenia (<100×109/L) |
– |
– |
– |
– |
+ |
|
Percentage of patientsa |
30 |
25 |
25 |
10 |
10 |
|
Median survival (years) |
12.5 |
8.4 |
6 |
1.5 |
|
|
a At the moment of diagnosis. | |||||
|
Based on Blood. 1975;46(2):219-34 and Ann Oncol. 2005;16 Suppl 1:i50-1. | |||||