Table 8.8-2. Binet classification of chronic lymphocytic leukemia

Stage

Percentage of patientsa

Clinical and hematological features

Median survival (years)

A

60

<3 areas of lymphoid enlargementa

>10

B

30

≥3 areas of lymphoid enlargementa

5

C

10

Anemia (hemoglobin <10 g/dL) or thrombocytopenia (<100,000/microL)

2

a Out of 5 areas: cervical lymph nodes (unilateral or bilateral), axillary lymph nodes, inguinal lymph nodes, spleen, liver.

Based on Cancer. 1977;40(2):855-64 and Ann Oncol. 2005;16 Suppl 1:i50-1.