Table 8.8-4. International prognostic index for non-Hodgkin lymphomas

International prognostic index (IPI) for aggressive NHL

Risk factors

Cutoff value

Age

≤60 years vs >60 years

ECOG performance status (see ecog-acrin.org)

<2 vs ≥2

Clinical stage (see Table 8.8-3)

I/II vs III/IV

Number of extranodal sites involved

≤1 vs >1

Serum LDH level

≤ULN vs >ULN

Risk groups

Number of risk factors

Low risk

≤1

Low-intermediate risk

2

High-intermediate risk

3

High risk

≥4

Follicular lymphoma-specific international prognostic index (FLIPI) for indolent NHL

Risk factors

Cutoff value

Age

≤60 years vs >60 years

Number of extranodal sites involved

≤4 vs >4

Clinical stage (see Table 8.8-3)

I/II vs III/IV

Hemoglobin level

<12 g/dL vs ≥12 g/dL

Serum LDH level

≤ULN vs >ULN

Risk groups

Number of risk factors

Low risk

≤1

Intermediate risk

2-3

High risk

4-5

ECOG, Eastern Cooperative Oncology Group; LDH, lactate dehydrogenase; NHL, non-Hodgkin lymphoma; ULN, upper limit of normal.