|
Feature |
Polycythemia vera |
Secondary erythrocytosis |
Relative erythrocytosis |
|
RBC mass |
↑ |
↑ |
N |
|
WBC count |
N or ↑ |
N |
N |
|
Platelet count |
N or ↑ |
N |
N |
|
Bone marrow |
Trilineage hyperplasia |
Erythropoietic lineage hyperplasia |
N |
|
Splenomegaly |
+++ |
– |
– |
|
Pruritus |
+/– |
– |
– |
|
SaO2 |
N |
N or ↓ |
N |
|
Serum vitamin B12 levels |
N or ↑ |
N |
N |
|
Granulocyte alkaline phosphatase |
↑ |
N |
N |
|
Serum erythropoietin levels |
↓ or N |
↑ |
N |
|
Endogenous growth of erythroid colonies |
+ |
– |
– |
|
↑, increased; ↓, decreased; N, normal; RBC, red blood cell; SaO2, direct measurement of hemoglobin oxygen saturation in arterial blood; WBC, white blood cell. | |||