Stage-3 defining opportunistic infections |
– Bacterial infections, multiple or recurrenta – Candidiasis of bronchi, trachea, or lungs – Candidiasis of esophagus – Cervical cancer, invasiveb – Coccidioidomycosis, disseminated or extrapulmonary – Cryptococcosis, extrapulmonary – Cryptosporidiosis, chronic intestinal (>1 month’s duration) – Cytomegalovirus disease (other than liver, spleen, or nodes), onset at age >1 month – Cytomegalovirus retinitis (with loss of vision) – Encephalopathy attributed to HIV – Herpes simplex: chronic ulcers (>1 month’s duration) or bronchitis, pneumonitis, or esophagitis (onset at age >1 month) – Histoplasmosis, disseminated or extrapulmonary – Isosporiasis, chronic intestinal (>1 month’s duration) – Kaposi sarcoma – Lymphoma, Burkitt (or equivalent term) – Lymphoma, immunoblastic (or equivalent term) – Lymphoma, primary, of brain – Mycobacterium avium complex or Mycobacterium kansasii, disseminated or extrapulmonary – Mycobacterium tuberculosis of any site, pulmonary,b disseminated, or extrapulmonary – Mycobacterium, other species or unidentified species, disseminated or extrapulmonary – Pneumocystis jiroveci (previously known as Pneumocystis carinii) pneumonia – Community-acquired pneumonia, recurrentb – Progressive multifocal leukoencephalopathy – Salmonella septicemia, recurrent – Toxoplasmosis of brain, onset at age >1 month – Wasting syndrome attributed to HIV |
Neoplastic diseases |
– Kaposi sarcoma – Lymphoma (Burkitt, primary lymphoma of brain, immunoblastic) – Invasive cervical carcinoma |
Clinical syndromes |
– HIV-related encephalopathy – HIV-related wasting |
a Only among children aged <6 years. b Only among adults, adolescents, and children aged ≥6 years. | |
Adapted from Centers for Disease Control and Prevention (CDC). Revised surveillance case definition for HIV infection--United States, 2014. MMWR Recomm Rep. 2014 Apr 11;63(RR-03):1-10. | |
AIDS, acquired immunodeficiency syndrome; HIV, human immunodeficiency virus. |