Beta-blocker |
Starting dose (mg)a |
Subsequent doses up to target dose (mg) |
Bisoprolol |
1.25 |
2.5 to 3.75 to 5 to 7.5 to 10 |
Carvedilol |
3.125 |
6.25 to 12.5 to 25 to 50 |
Metoprolol succinate controlled-release |
12.5 or 25 |
25 to 50 to 100 to 200 |
a Carvedilol is administered 2 times a day, while other listed beta-blockers are administered once daily. The table lists single doses of the agents. |