Agents and formulations |
Dosage | |
Beta-blockers | ||
Acebutolol |
400 mg once daily or 200 mg bid | |
Atenolol |
25-100 mg once daily | |
Betaxolol |
5-20 mg once daily | |
Bisoprolol |
2.5-10 mg once daily (max, 20 mg/d) | |
Celiprolola |
100-400 mg once daily | |
Carvedilol |
6.25-25 mg once daily or bid | |
Metoprolol | ||
Standard release Controlled release |
25-100 mg bid 50-100 mg once daily (up to 200 mg once daily) | |
Nebivolol |
5 mg once daily | |
Pindolol |
5-10 mg/d bid (doses up to 20 mg/d may be administered once daily; max, 60 mg/d) | |
Propranolol |
40-80 mg bid to qid | |
Calcium channel blockers (CCBs) | ||
Amlodipine |
2.5-10 mg once daily | |
Diltiazem | ||
Standard release Controlled release |
30-60 mg tid 90-480 mg once daily or 90-240 mg bid | |
Felodipine |
5-10 mg once daily | |
Isradipinea |
2.5-10 mg once daily or 5 mg bid | |
Lacidipinea |
4-6 mg once daily | |
Lercanidipinea |
10-20 mg once daily | |
Nitrendipinea |
10-20 mg once daily (max, 20 mg bid) | |
Verapamil | ||
Standard release Extended release |
40-120 mg tid to qid 120-240 mg once daily to bid | |
Diuretics | ||
Amiloride in a fixed-dose combination with hydrochlorothiazide |
2.5-5 mg once daily to bid | |
Chlorthalidone |
12.5-50 mg once daily or 50 mg every other day | |
Furosemide |
20-40 mg daily to bid (typically bid when used as an antihypertensive) | |
Hydrochlorothiazide |
12.5-50 mg once daily | |
Indapamide | ||
Standard release Extended release |
1.25-2.5 mg once daily 1.5 mg once daily | |
Clopamidea |
5-20 mg once daily | |
Spironolactone |
25-50 mg once daily to bid | |
Torasemidea |
2.5-10 mg once daily | |
Angiotensin-converting enzyme inhibitors (ACEIs) | ||
Benazepril |
5-20 mg once daily to bid | |
Quinapril |
5-40 mg once daily to bid | |
Cilazapril |
2.5-5 mg once daily | |
Enalapril |
2.5-20 mg once daily to bid (bid preferred) | |
Imidaprila |
5-20 mg once daily | |
Captopril |
25-50 mg bid to tid | |
Fosinopril |
10-40 mg daily | |
Lisinopril |
10-40 mg once daily | |
Perindopril |
4(5)-8(10) mg once daily | |
Ramipril |
2.5-5 mg once daily (max, 10 mg) | |
Trandolapril |
2-4 mg once daily | |
Zofenoprila |
30 mg once daily (up to 60 mg once daily or in 2 divided doses) | |
Angiotensin receptor blockers (ARBs) | ||
Eprosartan |
600 mg once daily | |
Irbesartan |
150-300 mg once daily | |
Candesartan |
8-32 mg once daily | |
Losartan |
25-100 mg once daily or in 2 divided doses | |
Telmisartan |
20-80 mg once daily | |
Valsartan |
80-320 mg once daily | |
a Not available in Canada. | ||
bid, 2 times a day; qid, 4 times a day; tid, 3 times a day. |