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Agents and formulations |
Dosage |
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Beta-blockers |
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Acebutolol |
400 mg once daily or 200 mg bid |
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Atenolol |
25-100 mg once daily |
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Betaxolol |
5-20 mg once daily |
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Bisoprolol |
2.5-10 mg once daily (max, 20 mg/d) |
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Celiprolola |
100-400 mg once daily |
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Carvedilol |
6.25-25 mg once daily or bid |
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| Metoprolol | ||
|
Standard release Controlled release |
25-100 mg bid 50-100 mg once daily (up to 200 mg once daily) |
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Nebivolol |
5 mg once daily |
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Pindolol |
5-10 mg/d bid (doses up to 20 mg/d may be administered once daily; max, 60 mg/d) |
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Propranolol |
40-80 mg bid to qid |
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Calcium channel blockers (CCBs) |
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Amlodipine |
2.5-10 mg once daily |
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| Diltiazem | ||
|
Standard release Controlled release |
30-60 mg tid 90-480 mg once daily or 90-240 mg bid |
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Felodipine |
5-10 mg once daily |
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Isradipinea |
2.5-10 mg once daily or 5 mg bid |
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Lacidipinea |
4-6 mg once daily |
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Lercanidipinea |
10-20 mg once daily |
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Nitrendipinea |
10-20 mg once daily (max, 20 mg bid) |
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| Verapamil | ||
|
Standard release Extended release |
40-120 mg tid to qid 120-240 mg once daily to bid |
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Diuretics |
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Amiloride in a fixed-dose combination with hydrochlorothiazide |
2.5-5 mg once daily to bid |
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Chlorthalidone |
12.5-50 mg once daily or 50 mg every other day |
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Furosemide |
20-40 mg daily to bid (typically bid when used as an antihypertensive) |
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Hydrochlorothiazide |
12.5-50 mg once daily |
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| Indapamide | ||
|
Standard release Extended release |
1.25-2.5 mg once daily 1.5 mg once daily |
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Clopamidea |
5-20 mg once daily |
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Spironolactone |
25-50 mg once daily to bid |
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Torasemidea |
2.5-10 mg once daily |
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Angiotensin-converting enzyme inhibitors (ACEIs) |
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Benazepril |
5-20 mg once daily to bid |
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Quinapril |
5-40 mg once daily to bid |
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Cilazapril |
2.5-5 mg once daily |
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Enalapril |
2.5-20 mg once daily to bid (bid preferred) |
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Imidaprila |
5-20 mg once daily |
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Captopril |
25-50 mg bid to tid |
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Fosinopril |
10-40 mg daily |
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Lisinopril |
10-40 mg once daily |
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Perindopril |
4(5)-8(10) mg once daily |
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Ramipril |
2.5-5 mg once daily (max, 10 mg) |
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Trandolapril |
2-4 mg once daily |
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Zofenoprila |
30 mg once daily (up to 60 mg once daily or in 2 divided doses) |
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Angiotensin receptor blockers (ARBs) |
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Eprosartan |
600 mg once daily |
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Irbesartan |
150-300 mg once daily |
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Candesartan |
8-32 mg once daily |
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Losartan |
25-100 mg once daily or in 2 divided doses |
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Telmisartan |
20-80 mg once daily |
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Valsartan |
80-320 mg once daily |
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a Not available in Canada. |
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bid, 2 times a day; qid, 4 times a day; tid, 3 times a day. |
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