GFR (mL/min/1.73 m2)

Serum potassium level (mmol/L)

After treatment initiation or dose change

In stable patientsa,b

≥60

≤4.5

In 2-4 weeks

Every 6-12 months

30-59

4.6-5

In 2-4 weeks

Every 3-6 months

<30

5.1-5.5

In 2 weeks

Every 2-4 months

a After determining dosage and stabilizing blood pressure, GFR, and serum potassium level.

b In patients with a GFR decrease ≥15% during ACEI or ARB treatment, measure serum creatinine levels (GFR) every 1-2 months.