Table 3.19-7. A modified Caprini risk assessment score

Risk factor

Score

Age

 

41-60 years

1

61-74 years

2

≥75 years

3

BMI >25 kg/m2

1

Women

 

Oral contraceptives or HRT

1

Pregnancy or postpartum

1

History of unexplained or recurrent miscarriage/stillborn infant

1

Thrombophilia

 

Elevated serum homocysteine

3

Positive factor V Leiden mutation

3

Positive prothrombin 20210A mutation

3

Positive lupus anticoagulant

3

Positive anticardiolipin antibodies

3

Positive anti–beta2-GPI antibodies

3

HIT

3

Other congenital or acquired thrombophilia

3

Venous disease

 

Lower limb edema

1

Varicose veins of lower limb

1

History of VTE

3

Family history of VTE

3

Immobilization

 

 

Medical patient currently at bed rest

1

Patient confined to bed (>72 h)

2

Limb immobilized in plaster cast

2

Surgery

 

Minor surgery planned

1

Arthroscopic surgery

2

Major surgery (>45 min)

2

Laparoscopic surgery (>45 min)

2

Elective arthroplasty

5

Hip, pelvis, or leg fracture

5

Other

 

Sepsis (<1 month)

1

Serious lung disease, including pneumonia (<1 month)

1

Abnormal pulmonary function

1

Acute myocardial infarction

1

Onset or exacerbation of heart failure (<1 month)

1

History of inflammatory bowel disease

1

Central venous access

2

Malignancy

2

Stroke (<1 month)

5

Acute spinal cord injury (<1 month)

5

Interpretation of risk level:

Score 0: Very low risk

Score 1-2: Low risk

Score 3-4: Moderate risk

Score ≥5: High risk

Adapted from Chest. 2012;141(2 Suppl):e227S-e277S.

Anti–beta2-GPI, anti–beta2-glycoprotein I; BMI, body mass index; HIT, heparin-induced thrombocytopenia; HRT, hormone replacement therapy; VTE, venous thromboembolism.