Table 3.11-14. Typical dosage of beta-blockers and calcium channel blockers in angina pectoris

Agent

Dosage (PO)

Beta-blockers

Acebutolol

200-600 mg bid

Atenolol

50-200 mg once daily

Betaxolol

10-20 mg once daily

Bisoprolol

5-10 mg once daily

Carvedilol

12.5-25 mg bid

Metoprolol

Immediate-release formulations

25-100 mg bid

Extended-release formulations

25-200 mg once daily

Pindolol

2.5-10 mg bid or tid

Propranolol

10-80 mg bid or tid

Dihydropyridine calcium channel blockers

Amlodipine

5-10 mg once daily

Felodipine

5-10 mg once daily

Nondihydropyridine calcium channel blockers

Diltiazem

 

Immediate-release formulations

30-90 mg tid

Extended-release formulations

120-480 mg once daily (or in 2 divided doses)

Verapamil

Immediate release formulations

40-160 mg tid

Extended-release formulations

120-480 mg once daily

bid, 2 times a day; tid, 3 times a day; PO, oral.