Nitroglycerin

(INN glyceryl trinitrate)

Aerosol

0.4 mg

1.5-7 min

Transdermal patch

5-20 mg/24 h

(patch should be detached for the night)

Prolonged-release tablets

6.5-15 mg bid

4-8 h

Isosorbide dinitrate

Tablets

5-10 mg

Up to 60 min

Isosorbide mononitrate

Tablets

10-40 mg bid

Up to 8 h

Prolonged-release tablets

50-100 mg once daily

12-24 h

Prolonged-release capsules

40-120 mg once daily

a In a long-term bid administration, the second dose should be administered within 8 h of the first dose (eg, 7:00 and 15:00), and the nitroglycerin patches should be detached for 10 h.