|
Risk of thrombosis associated with the prosthesis |
Examples of mechanical valves |
Target INR depending on the number of risk factorsa | |
|
No risk factors |
≥1 risk factor | ||
|
Low |
– Carbomedics (aortic) – Medtronic Hall – ATS – Medtronic Open Pivot – St. Jude Medical – Sorin Bicarbon |
2.5 |
3.0 |
|
Medium |
Other bileaflet valves |
3.0 |
3.5 |
|
High |
– Lillehei-Kaster – Omniscience – Starr-Edwards – Björk-Shiley – Other tilting disc valves |
3.5 |
4.0 |
|
a Risk factors: replacement of the mitral or tricuspid valve; prior thromboembolic event, atrial fibrillation, mitral stenosis of any severity, left ventricular ejection fraction <35%. | |||
|
Adapted from Eur Heart J. 2022 Feb 12;43(7):561-632. | |||
|
INR, international normalized ratio. | |||