Canadian Syncope Risk Score |
San Francisco Syncope Rule |
OESIL risk score |
Risk factors | ||
– Predisposition to vasovagal symptoms (−1) – Heart disease history (+1) – SBP <90 or >180 mm Hg (+2) – Elevated troponin (+2) – Abnormal QRS axis (+1) – QRS duration >130 ms (+1) – Corrected QT interval >480 ms (+2) – Vasovagal syncope (−2) – Cardiac syncope (+2) |
– SBP <90 mm Hg – Shortness of breath – ECG: nonsinus rhythm or new changes – Hematocrit <30% |
– Age >65 years – History of CVD – Syncope without prodrome – Abnormal ECG findings |
Assessed endpoint | ||
30-day morbidity and mortality after presentation to ED: |
7-day morbidity and mortality after presentation to ED: |
1-year mortality: |
– Score −3 to 0: 0.4%-1.9% – Score 1-3: 3.1%-8.1% – Score 4-5: 12.9%-19.7% – Score 6-11: 28.9%-83.6% |
– No factors present: 0.3% – ≥1 factor present: 15.2% |
– 0-1 factor (low risk): 0.6% – 2-4 factors (high risk): 31% |
Score accuracy | ||
– Score ≥−2: sensitivity 99%, specificity 26% – Score ≥−1: sensitivity 98%, specificity 46% |
– Sensitivity 98% – Specificity 56% – LR+: 2.9 – LR−: 0.03 |
– Sensitivity 97% – Specificity 73% – LR+: 3.6 – LR−: −0.11 |
Adapted from CMAJ. 2016;188(12):E289-98, Ann Emerg Med. 2004;43(2):224-32, and Eur Heart J. 2003;24(9):811-9. | ||
CVD, cardiovascular disease; ECG, electrocardiography; ED, emergency department; LR+, positive likelihood ratio; LR–, negative likelihood ratio; OESIL, Osservatorio Epidemiologico sulla Sincope nel Lazio; SBP, systolic blood pressure. |