Table 17.19-1. Strategies of PEEP/FiO2 adjustment in patients with acute respiratory distress syndrome

Lower PEEP strategy

FiO2

0.3-0.4

0.4-0.5

0.5-0.6

0.6-0.7

PEEP (cm H2O)

5

5-8

8-10

8-10

FiO2

0.7-0.8

0.8-0.9

0.9-1.0

1.0

PEEP (cm H2O)

10-14

14

14-18

18-24

Higher PEEP strategy

FiO2

0.3-0.4

0.4-0.5

0.5

0.5-0.8

PEEP (cm H2O)

5-14

14-16

16-18

18-20

FiO2

0.8-1.0

1.0

 

 

PEEP (cm H2O)

22

24

 

 

Adapted from ARDS Clinical Network. Mechanical ventilation protocol summary of low tidal volume used in the ALVEOLI study. http://www.ardsnet.org/tools.shtml.

FiO2, fraction of oxygen in the inspired air; PEEP, positive end-expiratory pressure.