Table 17.12-1. Tobacco use and cancer risk

Cancer site

Average relative risk

Lung

15.0-30.0

Urinary tract

3.0

Upper aerodigestive tract (larynx,a oral cavity, oropharynx and hypopharynx,a esophagus)

2.0-10.0

Esophagus (adenocarcinoma)

1.5-2.5

Pancreas

2.0-4.0

Nasal cavity, paranasal sinuses

1.5-2.5

Stomach

1.5-2.0

Kidney

1.5-2.0

Uterine cervix

1.5-2.5

Myeloid leukemia

1.5-2.0

a Synergistic interaction with alcohol use.

Adapted from J Natl Cancer Inst. 2004;96(2):99-106.