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For a brief introduction and guide to abbreviations, see Laboratory Tests: General Remarks.
Analyte [material]
Cardiac-specific troponins I and T (cTnI, cTnT) [S/P]
Reference range, target level, or decision threshold
cTnI: 9-80 ng/L (depending on method)!!!
cTnT: 9-22 ng/L (value diagnostic of significant myocardial damage)!!!
High-sensitivity cTnI and high-sensitivity cTnT assays are reported in ng/L and have sex-specific and pediatric-specific upper reference limits.
Interpretation of results
↑ Myocardial damage: MI, myocardial injury (mechanical, due to cardiac surgery, resuscitation, cardioversion/defibrillation), heart failure, hypertrophic cardiomyopathy, aortic dissection, aortic valve disease, PE, tachyarrhythmias, rhabdomyolysis with cardiac involvement, renal failure, stroke, subarachnoid hemorrhage, myocardial infiltrates (amyloidosis, hemochromatosis, sarcoidosis), sepsis, respiratory failure, burns, cardiotoxic drugs
