Interviews

McMaster Perspective more

SGLT2 inhibitors and kidney dysfunction
McMaster Perspective Extended
Dr Gordon Guyatt discusses the changing landscape of diabetes treatment, reviewing the latest high-quality evidence and offering insight into the effectiveness of SGLT2 inhibitors in patients with kidney dysfunction.
Blood pressure management after stroke
Dr Mike Sharma meets with Dr Roman Jaeschke to provide insights on blood pressure management in patients after stroke.

Antihypertensive drugs in AF
Which antihypertensive drugs should be recommended to patients with AF or other arrhythmias? With Dr Konstantinos Tsioufis.
Antihypertensive treatment in patients with BP <140/90 mm Hg
In which patients with BP <140/90 mm Hg would you recommend antihypertensive treatment? With Dr Maria Lorenza Muiesan.

Can DKA develop in type 2 diabetes?
Can diabetic ketoacidosis (DKA) develop in a patient with type 2 diabetes? With Dr René Rodríguez-Gutiérrez.
Current approaches to prediabetes
What are the current pharmacologic treatment options to delay the onset of type 2 diabetes in patients with prediabetes? With Dr Leszek Czupryniak.

Additional treatments in advanced liver diseases and elevated INR and/or thrombocytopenia
Should additional treatments (such as vitamin K or other agents) be initiated in patients with advanced liver disease and elevated INR and/or thrombocytopenia to prevent bleeding complications? With Dr Virginia Hernández-Gea.
Associations between H pylori infection and GERD
Is there any association between Helicobacter pylori infection and gastroesophageal reflux disease (GERD)? Should patients be tested for H pylori and receive eradication treatment if the results are positive before initiating proton pump inhibitors (PPIs)? With Dr Paul Moayyedi.

Do novel drugs allow us to discontinue glucocorticoids in HES?
Do novel drugs allow us to discontinue glucocorticoids in HES? With Dr Florence Roufosse.
How to differentiate between HES and EGPA?
How to differentiate between hypereosinophilic syndrome and eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome)? With Dr Florence Roufosse.

Antibiotic de-escalation in sepsis
When to discontinue or de-escalate antibiotics in patients with sepsis? With Dr Bram Rochwerg.
Composition of default fluid replacement solutions
What is the default fluid replacement solution that you use? Do you include potassium in your default IV fluid treatment? With Dr Simon Oczkowski.

Management in patients with rheumatic diseases treated with biologics prior to a travel to the tropics
How to manage a patient with a rheumatic disease on biologic drugs prior to a travel to the tropics? With Dr Somia Iqtadar.
Management of patients with fever during or after a travel to the tropics
How to manage a patient with fever during or after a travel to the tropics? With Dr Somia Iqtadar.

Administration of fluid therapy depending on kidney function
How to manage fluid therapy depending on the patient’s renal function? With Dr Jürgen Floege.
Finerenone and flozins in CKD
Would you say that finerenone has a comparable position as flozins in the treatment of patients with CKD? With Dr Jürgen Floege.

Management of patients with epilepsy
Could you please summarize the key advice for neurologists treating patients with drug-resistant epilepsy?
Cannabinoids in patients with epilepsy
What is the current place of cannabidiol and other cannabinoids in the treatment of epilepsy? How often are OTC cannabinoid preparations used by patients with epilepsy in North America? How does it affect the clinical management of epilepsy?

The 3 most important recent advances in treating cancer pain with opioids
Dr Per Sjøgren from University of Copenhagen, Denmark, shares his views on the 3 most important recent advances in treating cancer pain with opioids.
CA 19-9 in pancreatic cancer screening
What is the role of cancer antigen (CA) 19-9 in screening for pancreatic cancer?

Biologics and remission of asthma
Can the biologic treatment used in asthma promote permanent remission of the disease? With Dr Paul O'Byrne.
Biosimilar drugs and burden of severe asthma
To what degree does the introduction of biosimilar drugs into the asthma treatment regimens reduce the burden of severe asthma? With Dr Paul O’Byrne.

Assessment of the risk of falls
How to assess the risk of falls in everyday practice? With Dr Jyotirmoy Pal.
Diagnostic workup of GCA in individuals with PMR
Which diagnostic approach would be the most useful and proper to detect subclinical GCA in a patient with PMR to avoid relapse after discontinuing or tapering glucocorticoids? With Dr Bhaskar Dasgupta.

Medical cannabis and abuse of psychoactive cannabinoids
Is there a risk that the legal use of medical cannabis will affect the abuse of psychoactive cannabinoids?
Medical cannabis and alcohol or drug addiction
Can we use medical cannabis in patients with alcohol or drug addiction?

Clinical scenarios for reduced-dose anticoagulants
Can you think of any clinical scenarios when we should consider using a reduced dose of an anticoagulant? With Dr James Douketis.
Recent advances in bleeding management
What are the recent advances in the management of bleeding in 2024? With Dr James Douketis.

Age and comorbidities vs choice of antibiotics
Should age and comorbidities be taken into account when making decisions about the choice of antibiotics? With Dr Annette Kurrle.
AI in medicine: Are there any risks?
What do you consider the biggest dangers of artificial intelligence in medicine? With Dr Dan Perri.