Anti−Thyroperoxidase Antibodies (TPOAb)

How to Cite This Chapter: Don-Wauchope A, Chetty VT, Ivica J, Kavsak P, Khan WI, Lafreniere M, Nouri K, Solnica B. Anti−Thyroperoxidase Antibodies (TPOAb). McMaster Textbook of Internal Medicine. Kraków: Medycyna Praktyczna. https://empendium.com/mcmtextbook/chapter/B31.1269.3.7.166. Accessed May 26, 2024.
Last Updated: May 9, 2022
Last Reviewed: May 9, 2022
Chapter Information

For a brief introduction and guide to abbreviations, see Laboratory Tests: General Remarks.

Analyte [material]

Anti−thyroperoxidase antibodies (TPOAb) [S/P]

Reference range, target level, or decision threshold

<34 IU/mL (depending on method)!!!; CW

Interpretation of results

↑ Chronic autoimmune thyroiditis (Hashimoto thyroiditis), Graves disease (↑ TRAb confirms the diagnosis), primary hypothyroidism, healthy individuals

Do not routinely measure TPOAb.

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