Apolipoprotein B (ApoB)

For a brief introduction and guide to abbreviations, see Laboratory Tests: General Remarks.

Analyte [material]

Apolipoprotein B (ApoB) [S/P]

Reference range, target level, or decision threshold

Depends on cardiovascular riskCPG:

Extremely high: <55 mg/dL

Very high: <65 mg/dL

High: <80 mg/dL

Moderate: <100 mg/dL

There are age-specific reference intervals for pediatric patients.

Interpretation of results

↑ Familial hypercholesterolemia, familial apolipoprotein B100 deficiency, polygenic hypercholesterolemia, hypothyroidism, nephrotic syndrome, CKD, liver diseases with cholestasis, drugs (progestogens, glucocorticoids, protease inhibitors used in HIV infection)

↓ Hyperthyroidism, advanced cirrhosis and other severe liver injury, sepsis, cachexia