Apolipoprotein B (ApoB)

How to Cite This Chapter: Don-Wauchope A, Chetty VT, Ivica J, Kavsak P, Khan WI, Lafreniere M, Nouri K, Solnica B. Apolipoprotein B (ApoB). McMaster Textbook of Internal Medicine. Kraków: Medycyna Praktyczna. https://empendium.com/mcmtextbook/chapter/B31.1269.3.7.174. Accessed May 24, 2024.
Last Updated: May 9, 2022
Last Reviewed: May 9, 2022
Chapter Information

For a brief introduction and guide to abbreviations, see Laboratory Tests: General Remarks.

Analyte [material]

Apolipoprotein B (ApoB) [S/P]

Reference range, target level, or decision threshold

Depends on cardiovascular riskCPG:

Extremely high: <55 mg/dL

Very high: <65 mg/dL

High: <80 mg/dL

Moderate: <100 mg/dL

There are age-specific reference intervals for pediatric patients.

Interpretation of results

↑ Familial hypercholesterolemia, familial apolipoprotein B100 deficiency, polygenic hypercholesterolemia, hypothyroidism, nephrotic syndrome, CKD, liver diseases with cholestasis, drugs (progestogens, glucocorticoids, protease inhibitors used in HIV infection)

↓ Hyperthyroidism, advanced cirrhosis and other severe liver injury, sepsis, cachexia

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