Chloride (Cl–)

How to Cite This Chapter: Don-Wauchope A, Chetty VT, Ivica J, Kavsak P, Khan WI, Lafreniere M, Nouri K, Solnica B. Chloride (Cl). McMaster Textbook of Internal Medicine. Kraków: Medycyna Praktyczna. https://empendium.com/mcmtextbook/chapter/B31.1269.3.7.177. Accessed December 05, 2025.
Last Reviewed: May 9, 2022
Last Updated: May 9, 2022
Chapter Information

For a brief introduction and guide to abbreviations, see Laboratory Tests: General Remarks.

Analyte [material]

Chloride (Cl) [S/P]

Reference range, target level, or decision threshold

98-106 mmol/L

Interpretation of results

↑ Hypertonic dehydration, excessive NaCl intake, metabolic acidosis due to HCO3 loss

↓ Hyponatremia, Cl loss due to vomiting or diarrhea

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