Collagen Type I alpha Chain (NTx), N‑Terminal Telopeptide

How to Cite This Chapter: Don-Wauchope A, Chetty VT, Ivica J, Kavsak P, Khan WI, Lafreniere M, Nouri K, Solnica B. N‑terminal Telopeptide of Type I Collagen Alpha Chain (NTx). McMaster Textbook of Internal Medicine. Kraków: Medycyna Praktyczna. https://empendium.com/mcmtextbook/chapter/B31.1269.3.7.186. Accessed December 05, 2025.
Last Reviewed: May 9, 2022
Last Updated: May 9, 2022
Chapter Information

For a brief introduction and guide to abbreviations, see Laboratory Tests: General Remarks.

Analyte [material]

N–terminal telopeptide of type I collagen alpha chain (NTx) [U]

Reference range, target level, or decision threshold

<60 nmol bone collagen equivalents (BCE)!!!

Interpretation of results

↑ Bone diseases: Osteoporosis, osteomalacia, primary hyperparathyroidism, CKD, vitamin D deficiency, metastases

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