Calprotectin

How to Cite This Chapter: Don-Wauchope A, Chetty VT, Ivica J, Kavsak P, Khan WI, Lafreniere M, Nouri K, Solnica B. Calprotectin. McMaster Textbook of Internal Medicine. Kraków: Medycyna Praktyczna. https://empendium.com/mcmtextbook/chapter/B31.1269.3.7.190. Accessed December 05, 2025.
Last Reviewed: May 9, 2022
Last Updated: May 9, 2022
Chapter Information

For a brief introduction and guide to abbreviations, see Laboratory Tests: General Remarks.

Analyte [material]

Calprotectin [stool]

Reference range, target level, or decision threshold

<50 microg/g

Interpretation of results

>250 microg/g: IBD, GI infections, GI tract malignancies, colonic diverticulosis, use of NSAIDs

50-250 microg/g: Cirrhosis, microscopic colitis, celiac disease and other enteropathies, PUD, gastritis, reflux esophagitis, food allergy, small intestinal bacterial overgrowth, use of PPIs

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