How to Cite This Chapter: Don-Wauchope A, Chetty VT, Ivica J, Kavsak P, Khan WI, Lafreniere M, Nouri K, Solnica B. Neutrophils. McMaster Textbook of Internal Medicine. Kraków: Medycyna Praktyczna. Accessed May 26, 2024.
Last Updated: May 9, 2022
Last Reviewed: May 9, 2022
Chapter Information

For a brief introduction and guide to abbreviations, see Laboratory Tests: General Remarks.

Analyte [material]


Reference range, target level, or decision threshold

1800-8000/microL (1.8-8 Giga/L), 60%-70%

Interpretation of results

↑ Acute bacterial infection, certain viral infections, myeloproliferative neoplasms, rarely Hodgkin lymphoma or solid tumors, excessive glucocorticoid levels (Cushing syndrome), systemic connective tissue diseases (rheumatoid arthritis, Still disease, SLE, systemic vasculitis), IBD, acute tissue inflammation or necrosis (gout flare, reactive arthritis, burns, MI, rheumatic fever, acute pancreatitis), trauma, surgery, shock, heatstroke, seizures, after massive hemorrhage, acute hemolysis, tobacco smoking, diabetic ketoacidosis, thyroid storm, use of growth factors or catecholamines, after splenectomy, bone marrow regeneration (eg, after chemotherapy), certain poisonings (eg, with heavy metals), after meal, after exercise, pregnancy, delivery

↓ Aplastic anemia, acute leukemias, myelodysplastic syndromes, myelofibrosis, after infections (particularly viral infections and bacterial sepsis), certain infections (TB, brucellosis, enteric fever), systemic connective tissue diseases, hypersplenism, drugs (eg, cytostatic, thyreostatic, antiepileptic, and psychotropic agents), congenital neutropenia and radiotherapy, vitamin B12 or folate deficiencies, chronic benign neutropenia (autoimmune or idiopathic), benign ethnic neutropenia

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